Basic Information
ID: ALA4027198
Type: Binding
Description: Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS at 2.5 uM using 2-thio-PAF as substrate preincubated for 30 min followed by substrate addition measured every minute for 10 mins by DNTB reagent based assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4027198
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.55 | 5.24 | 5.24 |
| 446.53 | 5.70 | 5.70 |
| 432.50 | 5.39 | 5.39 |
| 500.50 | 6.41 | 6.41 |
| 466.95 | 6.04 | 6.04 |
| 457.51 | 5.26 | 5.26 |
| 473.58 | 5.62 | 5.62 |
| 462.53 | 5.40 | 5.40 |
| 456.53 | 5.21 | 5.21 |
| 450.49 | 5.53 | 5.53 |