Basic Information
ID: ALA4027226
Type: Binding
Description: Inhibition of PDE4 in human PBMC assessed as reduction in LPS-induced TNFalpha release after 18 hrs by quantitative ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4027226
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.24 | 4.29 | 4.29 |
| 676.55 | 5.00 | 5.00 |
| 657.54 | 4.20 | 4.20 |
| 746.64 | 5.31 | 5.31 |
| 758.62 | 5.41 | 5.41 |
| 657.52 | 5.70 | 5.70 |
| 717.57 | 5.71 | 5.71 |
| 746.64 | 5.31 | 5.31 |
| 710.58 | 5.76 | 5.76 |
| 671.55 | 6.09 | 6.09 |
| 735.61 | 5.63 | 5.63 |
| 746.64 | 5.31 | 5.31 |
| 595.45 | 4.27 | 4.27 |
| 760.66 | 5.84 | 5.84 |
| 709.64 | 6.29 | 6.29 |
| 621.49 | 4.78 | 4.78 |
| 692.55 | 4.23 | 4.23 |
| 679.55 | 4.34 | 4.34 |
| 326.37 | 0.63 | 0.63 |
| 728.60 | 5.40 | 5.40 |
| 742.62 | 5.79 | 5.79 |
| 728.60 | 5.40 | 5.40 |
| 776.66 | 5.32 | 5.32 |
| 657.52 | 5.70 | 5.70 |
| 746.64 | 5.31 | 5.31 |
| 772.65 | 5.80 | 5.80 |
| 735.61 | 4.31 | 4.31 |
| 706.57 | 4.53 | 4.53 |
| 344.41 | 0.54 | 0.54 |
| 675.56 | 5.61 | 5.61 |
| 639.50 | 4.28 | 4.28 |
| 746.64 | 5.31 | 5.31 |
| 742.62 | 5.65 | 5.65 |