Basic Information
ID: ALA4027387
Type: Binding
Description: Antagonist activity at NMDA receptor in Nras driven p53 deficient mouse HCC cell membranes assessed as decrease in Abcb1/Abcg2 protein expression levels by measuring sorafenib accumulation at 10 uM preincubated for 24 hrs followed by compound wash out and addition of sorafenib measured after 30 mins by LC/MS-MS method relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4027387
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 306.14 | 1.57 | 1.57 |