Assay Report Card

Basic Information

ID: ALA4027388

Type: Binding

Description: Antagonist activity at NMDA receptor in Nras driven p53 deficient mouse HCC cell membranes assessed as decrease in Slc2a1 protein expression levels by measuring [14C]-D-glucose accumulation at 10 uM preincubated for 24 hrs followed by compound wash out and addition of [14C]-D-glucose measured after 5 mins by scintillation counting method relative to control

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
306.141.571.57