Assay Report Card

Basic Information

ID: ALA4027408

Type: Functional

Description: Antitumor activity against human KARPAS422 cells harboring EZH2 Y641N mutant xenografted in mouse assessed as decrease in tumor regression at 100 mg/kg, sc qd measured 40 days post treatment termination on day 31

Organism: Homo sapiens

Cell type: KARPAS-422

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
467.353.533.53