Basic Information
ID: ALA4027525
Type: Binding
Description: Inhibition of ACC1 in human HCT116 cells assessed as reduction of [14C]acetate uptake preincubated for 60 mins followed by addition of [14C]acetate and measured after 2 hrs by scintillation counting analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4027525
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.50 | 5.67 | 5.67 |
| 365.43 | 3.60 | 3.60 |
| 431.53 | 6.04 | 6.04 |
| 422.48 | 4.83 | 4.83 |
| 423.51 | 4.47 | 4.47 |
| 423.47 | 4.22 | 4.22 |
| 449.55 | 4.86 | 4.86 |
| 423.47 | 4.36 | 4.36 |
| 443.50 | 5.67 | 5.67 |
| 421.54 | 5.03 | 5.03 |
| 457.60 | 7.35 | 7.35 |
| 422.48 | 4.83 | 4.83 |
| 421.50 | 4.08 | 4.08 |
| 423.47 | 4.22 | 4.22 |
| 420.51 | 5.38 | 5.38 |
| 442.52 | 6.27 | 6.27 |
| 459.57 | 6.14 | 6.14 |