Basic Information
ID: ALA4027836
Type: Binding
Description: Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4027836
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.40 | 3.17 | 3.17 |
| 291.31 | 2.70 | 2.70 |
| 399.24 | 4.08 | 4.08 |
| 371.37 | 2.77 | 2.77 |
| 369.76 | 3.87 | 3.87 |
| 320.35 | 3.81 | 3.81 |
| 306.32 | 3.01 | 3.01 |
| 293.33 | 2.95 | 2.95 |
| 305.34 | 2.89 | 2.89 |
| 339.78 | 3.54 | 3.54 |
| 317.39 | 4.06 | 4.06 |
| 274.32 | 4.00 | 4.00 |
| 399.24 | 4.08 | 4.08 |
| 307.31 | 3.90 | 3.90 |
| 400.50 | 3.05 | 3.05 |
| 304.35 | 4.01 | 4.01 |
| 288.35 | 4.31 | 4.31 |
| 324.30 | 2.55 | 2.55 |
| 340.40 | 3.00 | 3.00 |
| 320.35 | 3.71 | 3.71 |
| 295.30 | 2.34 | 2.34 |
| 306.32 | 3.01 | 3.01 |
| 341.21 | 4.75 | 4.75 |
| 326.38 | 2.86 | 2.86 |