Basic Information
ID: ALA4028145
Type: Binding
Description: Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction in aldosterone-induced luciferase activity after 16 hrs in presence of serum by luciferase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4028145
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.37 | 2.38 | 2.38 |
| 355.39 | 2.01 | 2.01 |
| 310.35 | 2.60 | 2.60 |
| 325.37 | 2.38 | 2.38 |
| 343.36 | 2.52 | 2.52 |
| 325.37 | 2.38 | 2.38 |
| 343.36 | 2.52 | 2.52 |
| 311.34 | 1.99 | 1.99 |
| 326.36 | 1.77 | 1.77 |
| 341.37 | 1.35 | 1.35 |
| 339.39 | 2.77 | 2.77 |
| 343.36 | 2.52 | 2.52 |
| 324.38 | 2.98 | 2.98 |
| 325.37 | 2.38 | 2.38 |
| 350.38 | 2.27 | 2.27 |