Basic Information
ID: ALA4028680
Type: Binding
Description: Inhibition of Clostridium botulinum BoNT/A holotoxin-mediated SNAP-25 cleavage in mouse HBG3 cell-derived motor neurons assessed as full length of SNAP-25 at 10 uM preincubated for 30 mins followed by intoxication measured after 4 hrs by Western blot method relative to control
Organism: Clostridium botulinum
Activity Charts
Bioactivity
Activity Types for Assay ALA4028680
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 998.24 | 13.44 | 13.44 |
| 415.98 | 6.02 | 6.02 |
| 381.54 | 5.37 | 5.37 |
| 430.01 | 6.41 | 6.41 |
| 395.57 | 5.76 | 5.76 |
| 516.71 | 8.26 | 8.26 |
| 490.68 | 7.75 | 7.75 |
| 689.00 | 7.89 | 7.89 |
| 703.03 | 8.23 | 8.23 |
| 363.55 | 5.19 | 5.19 |
| 674.97 | 7.50 | 7.50 |
| 377.58 | 5.62 | 5.62 |
| 469.63 | 7.58 | 7.58 |
| 462.62 | 6.97 | 6.97 |
| 397.99 | 5.84 | 5.84 |
| 544.77 | 9.04 | 9.04 |
| 490.68 | 7.70 | 7.70 |
| 469.63 | 7.63 | 7.63 |
| 516.71 | 8.26 | 8.26 |
| 469.63 | 7.63 | 7.63 |
| 689.00 | 7.84 | 7.84 |
| 709.42 | 8.16 | 8.16 |
| 689.00 | 7.89 | 7.89 |
| 377.58 | 5.57 | 5.57 |
| 476.65 | 7.36 | 7.36 |
| 412.02 | 6.23 | 6.23 |
| 558.80 | 9.39 | 9.39 |
| 397.99 | 5.88 | 5.88 |
| 625.34 | 7.01 | 7.01 |
| 488.66 | 7.48 | 7.48 |