Assay Report Card

Basic Information

ID: ALA4028685

Type: Binding

Description: Inhibition of Clostridium botulinum BoNT/A holotoxin-mediated SNAP-25 cleavage in mouse HBG3 cell-derived motor neurons assessed as full length of SNAP-25 at 20 uM treated at 30 mins post intoxication by Western blot method relative to control

Organism: Clostridium botulinum

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
998.2413.4413.44
689.007.897.89
674.977.507.50
397.995.845.84
544.779.049.04
469.637.637.63
709.428.168.16
689.007.897.89
412.026.236.23
558.809.399.39