Assay Report Card

Basic Information

ID: ALA4029018

Type: ADME

Description: Stimulation of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and GSH measured after 20 mins by membrane vesicle transport assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
383.411.781.78
357.793.933.93
441.554.374.37
284.753.153.15
398.403.703.70
250.343.573.57
494.013.643.64
356.424.374.37
356.453.163.16
357.442.492.49
351.411.951.95
454.913.963.96
371.872.362.36
323.130.910.91
272.393.613.61
551.634.204.20
461.014.274.27
364.423.043.04
334.172.892.89
354.193.913.91
326.445.175.17
273.242.552.55
527.643.523.52
207.272.442.44
548.633.483.48
490.633.073.07
366.504.314.31
428.544.784.78
430.552.772.77
360.372.572.57
438.522.572.57
335.342.352.35
289.163.593.59
581.475.755.75
558.604.174.17
408.332.362.36
341.504.264.26
319.844.414.41
411.474.634.63