ID: ALA4029018
Type: ADME
Description: Stimulation of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and GSH measured after 20 mins by membrane vesicle transport assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4029018
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
383.41 | 1.78 | 1.78 |
357.79 | 3.93 | 3.93 |
441.55 | 4.37 | 4.37 |
284.75 | 3.15 | 3.15 |
398.40 | 3.70 | 3.70 |
250.34 | 3.57 | 3.57 |
494.01 | 3.64 | 3.64 |
356.42 | 4.37 | 4.37 |
356.45 | 3.16 | 3.16 |
357.44 | 2.49 | 2.49 |
351.41 | 1.95 | 1.95 |
454.91 | 3.96 | 3.96 |
371.87 | 2.36 | 2.36 |
323.13 | 0.91 | 0.91 |
272.39 | 3.61 | 3.61 |
551.63 | 4.20 | 4.20 |
461.01 | 4.27 | 4.27 |
364.42 | 3.04 | 3.04 |
334.17 | 2.89 | 2.89 |
354.19 | 3.91 | 3.91 |
326.44 | 5.17 | 5.17 |
273.24 | 2.55 | 2.55 |
527.64 | 3.52 | 3.52 |
207.27 | 2.44 | 2.44 |
548.63 | 3.48 | 3.48 |
490.63 | 3.07 | 3.07 |
366.50 | 4.31 | 4.31 |
428.54 | 4.78 | 4.78 |
430.55 | 2.77 | 2.77 |
360.37 | 2.57 | 2.57 |
438.52 | 2.57 | 2.57 |
335.34 | 2.35 | 2.35 |
289.16 | 3.59 | 3.59 |
581.47 | 5.75 | 5.75 |
558.60 | 4.17 | 4.17 |
408.33 | 2.36 | 2.36 |
341.50 | 4.26 | 4.26 |
319.84 | 4.41 | 4.41 |
411.47 | 4.63 | 4.63 |