Basic Information
ID: ALA4029489
Type: Binding
Description: Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot method
Format: BAO_0000219
Organism: Homo sapiens
Target: Cell division protein kinase 8(ALA5719)
Document: ALA4028808
Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4029489
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 283.40 | 3.39 | 3.39 |
| 283.40 | 2.19 | 2.19 |
| 343.43 | 3.56 | 3.56 |
| 372.43 | 2.36 | 2.36 |
| 358.45 | 3.30 | 3.30 |
| 329.41 | 3.26 | 3.26 |
| 343.43 | 3.56 | 3.56 |
| 296.44 | 3.05 | 3.05 |
| 279.39 | 2.07 | 2.07 |
| 400.49 | 2.96 | 2.96 |
| 349.46 | 3.93 | 3.93 |
| 430.51 | 2.63 | 2.63 |
| 266.35 | 2.32 | 2.32 |
| 266.35 | 2.08 | 2.08 |
| 343.43 | 3.56 | 3.56 |
| 444.54 | 2.94 | 2.94 |
| 343.43 | 3.56 | 3.56 |
| 359.50 | 4.34 | 4.34 |
| 344.42 | 2.84 | 2.84 |
| 386.46 | 2.62 | 2.62 |
| 444.54 | 3.02 | 3.02 |
| 282.42 | 2.79 | 2.79 |
| 264.40 | 3.56 | 3.56 |
| 328.42 | 3.86 | 3.86 |
| 310.47 | 3.39 | 3.39 |
| 365.53 | 4.40 | 4.40 |
| 386.46 | 3.21 | 3.21 |
| 359.43 | 2.80 | 2.80 |
| 265.36 | 2.06 | 2.06 |
| 444.54 | 2.76 | 2.76 |
| 279.39 | 2.07 | 2.07 |
| 329.41 | 3.26 | 3.26 |
| 362.51 | 3.68 | 3.68 |
| 314.41 | 1.47 | 1.47 |
| 358.51 | 4.94 | 4.94 |
| 298.41 | 1.81 | 1.81 |