Assay Report Card

Basic Information

ID: ALA4029856

Type: Binding

Description: Inhibition of recombinant human mPGES-1 expressed in CHO cells assessed as reduction in PGE2 formation at 1 uM using PGH2 a substrate preincubated for 10 mins followed by substrate addition measured after 1 min relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
468.586.556.55
515.897.437.43
488.877.737.73
453.956.236.23
488.877.737.73
444.906.716.71
436.876.096.09
407.675.935.93
454.675.775.77
532.327.637.63
515.897.437.43
472.877.857.85
468.946.186.18
513.036.666.66
439.327.487.48
515.877.127.12
500.337.217.21
472.877.857.85