ID: ALA4029856
Type: Binding
Description: Inhibition of recombinant human mPGES-1 expressed in CHO cells assessed as reduction in PGE2 formation at 1 uM using PGH2 a substrate preincubated for 10 mins followed by substrate addition measured after 1 min relative to control
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4029856
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
468.58 | 6.55 | 6.55 |
515.89 | 7.43 | 7.43 |
488.87 | 7.73 | 7.73 |
453.95 | 6.23 | 6.23 |
488.87 | 7.73 | 7.73 |
444.90 | 6.71 | 6.71 |
436.87 | 6.09 | 6.09 |
407.67 | 5.93 | 5.93 |
454.67 | 5.77 | 5.77 |
532.32 | 7.63 | 7.63 |
515.89 | 7.43 | 7.43 |
472.87 | 7.85 | 7.85 |
468.94 | 6.18 | 6.18 |
513.03 | 6.66 | 6.66 |
439.32 | 7.48 | 7.48 |
515.87 | 7.12 | 7.12 |
500.33 | 7.21 | 7.21 |
472.87 | 7.85 | 7.85 |