Basic Information
ID: ALA4029857
Type: Binding
Description: Inhibition of recombinant human mPGES-1 expressed in CHO cells assessed as reduction in PGE2 formation at 10 uM using PGH2 a substrate preincubated for 10 mins followed by substrate addition measured after 1 min relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4029857
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 468.58 | 6.55 | 6.55 |
| 515.89 | 7.43 | 7.43 |
| 488.87 | 7.73 | 7.73 |
| 453.95 | 6.23 | 6.23 |
| 488.87 | 7.73 | 7.73 |
| 444.90 | 6.71 | 6.71 |
| 436.87 | 6.09 | 6.09 |
| 407.67 | 5.93 | 5.93 |
| 454.67 | 5.77 | 5.77 |
| 532.32 | 7.63 | 7.63 |
| 515.89 | 7.43 | 7.43 |
| 472.87 | 7.85 | 7.85 |
| 468.94 | 6.18 | 6.18 |
| 513.03 | 6.66 | 6.66 |
| 439.32 | 7.48 | 7.48 |
| 515.87 | 7.12 | 7.12 |
| 500.33 | 7.21 | 7.21 |
| 472.87 | 7.85 | 7.85 |