Basic Information
ID: ALA4029858
Type: Binding
Description: Inhibition of recombinant human mPGES-1 expressed in CHO cells assessed as reduction in PGE2 formation using PGH2 a substrate preincubated for 10 mins followed by substrate addition measured after 1 min
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4029858
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.82 | 5.93 | 5.93 |
| 496.89 | 7.58 | 7.58 |
| 449.94 | 6.33 | 6.33 |
| 463.34 | 7.22 | 7.22 |
| 497.88 | 6.98 | 6.98 |
| 468.58 | 6.55 | 6.55 |
| 532.32 | 7.63 | 7.63 |
| 481.33 | 7.36 | 7.36 |
| 512.47 | 6.67 | 6.67 |
| 515.89 | 7.43 | 7.43 |
| 514.88 | 7.72 | 7.72 |
| 488.87 | 7.73 | 7.73 |
| 497.78 | 7.87 | 7.87 |
| 463.34 | 7.22 | 7.22 |
| 514.88 | 7.72 | 7.72 |
| 497.88 | 6.98 | 6.98 |
| 426.48 | 5.51 | 5.51 |
| 447.87 | 6.10 | 6.10 |
| 514.33 | 7.49 | 7.49 |
| 528.92 | 7.19 | 7.19 |
| 514.88 | 7.72 | 7.72 |
| 531.34 | 8.24 | 8.24 |
| 495.37 | 6.82 | 6.82 |
| 496.89 | 7.58 | 7.58 |
| 532.32 | 7.63 | 7.63 |
| 428.89 | 6.56 | 6.56 |
| 472.87 | 7.85 | 7.85 |
| 496.89 | 7.58 | 7.58 |
| 531.34 | 8.24 | 8.24 |
| 463.34 | 7.22 | 7.22 |
| 497.78 | 7.87 | 7.87 |
| 513.03 | 6.66 | 6.66 |
| 548.78 | 8.15 | 8.15 |
| 497.78 | 7.87 | 7.87 |
| 514.88 | 7.72 | 7.72 |
| 497.88 | 6.98 | 6.98 |
| 510.48 | 6.41 | 6.41 |
| 512.89 | 7.46 | 7.46 |
| 494.48 | 6.53 | 6.53 |
| 500.33 | 7.21 | 7.21 |
| 430.87 | 5.35 | 5.35 |
| 472.87 | 7.85 | 7.85 |