Basic Information
ID: ALA4029859
Type: Binding
Description: Inhibition of mPGES-1 in human A549 cells assessed as decrease in IL1beta induced PGE2 release preincubated for 30 mins followed by IL-1beta addition after 16 to 20 hrs by HTRF method
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA4029859
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.82 | 5.93 | 5.93 |
| 481.33 | 7.36 | 7.36 |
| 512.47 | 6.67 | 6.67 |
| 514.88 | 7.72 | 7.72 |
| 488.87 | 7.73 | 7.73 |
| 514.88 | 7.72 | 7.72 |
| 426.48 | 5.51 | 5.51 |
| 528.92 | 7.19 | 7.19 |
| 514.88 | 7.72 | 7.72 |
| 531.34 | 8.24 | 8.24 |
| 495.37 | 6.82 | 6.82 |
| 496.89 | 7.58 | 7.58 |
| 497.78 | 7.87 | 7.87 |
| 514.88 | 7.72 | 7.72 |
| 510.48 | 6.41 | 6.41 |
| 512.89 | 7.46 | 7.46 |
| 494.48 | 6.53 | 6.53 |
| 472.87 | 7.85 | 7.85 |