Basic Information
ID: ALA4029861
Type: ADME
Description: Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 insect cells assessed as decrease in PGE2 release using arachidonic acid as substrate preincubated for 15 mins followed by arachidonic acid addition measured after 5 mins
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4029861
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.33 | 7.36 | 7.36 |
| 488.87 | 7.73 | 7.73 |
| 472.87 | 7.85 | 7.85 |