Basic Information
ID: ALA4029883
Type: ADME
Description: Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 insect cells assessed as decrease in PGE2 release at 1 uM using arachidonic acid as substrate preincubated for 15 mins followed by arachidonic acid addition measured after 5 mins relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4029883
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 488.87 | 7.73 | 7.73 |
| 472.87 | 7.85 | 7.85 |