Assay Report Card

Basic Information

ID: ALA4029884

Type: ADME

Description: Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 insect cells assessed as decrease in PGE2 release at 10 uM using arachidonic acid as substrate preincubated for 15 mins followed by arachidonic acid addition measured after 5 mins relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
488.877.737.73
472.877.857.85