Basic Information
ID: ALA4029973
Type: ADME
Description: Inhibition of human CYP11B1-8C7 expressed in Chinese hamster V79 cells using 11-deoxycortisol as substrate preincubated for 1 hr followed by substrate addition measured for 3 hrs by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4029973
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 267.33 | 2.96 | 2.96 |
| 287.75 | 3.30 | 3.30 |
| 243.24 | 2.57 | 2.57 |
| 321.30 | 3.67 | 3.67 |
| 213.22 | 2.56 | 2.56 |
| 289.29 | 2.93 | 2.93 |
| 283.33 | 2.66 | 2.66 |
| 375.27 | 4.21 | 4.21 |
| 321.30 | 3.67 | 3.67 |
| 321.30 | 3.67 | 3.67 |
| 271.30 | 2.79 | 2.79 |
| 287.75 | 3.30 | 3.30 |
| 321.30 | 3.67 | 3.67 |
| 281.21 | 3.58 | 3.58 |
| 321.30 | 3.50 | 3.50 |
| 285.32 | 3.10 | 3.10 |
| 271.30 | 2.79 | 2.79 |
| 267.33 | 2.96 | 2.96 |
| 253.31 | 2.65 | 2.65 |
| 271.30 | 2.79 | 2.79 |
| 231.21 | 2.70 | 2.70 |
| 311.34 | 2.43 | 2.43 |
| 271.30 | 2.79 | 2.79 |
| 271.25 | 2.35 | 2.35 |
| 305.74 | 3.44 | 3.44 |
| 321.30 | 3.50 | 3.50 |
| 293.37 | 3.53 | 3.53 |
| 278.32 | 2.52 | 2.52 |
| 283.33 | 2.66 | 2.66 |
| 267.33 | 2.96 | 2.96 |
| 325.26 | 3.33 | 3.33 |