Basic Information
ID: ALA4030011
Type: Binding
Description: Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4030011
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.54 | 3.15 | 3.15 |
| 452.51 | 1.31 | 1.31 |
| 466.54 | 1.62 | 1.62 |
| 429.50 | 2.65 | 2.65 |
| 475.55 | 2.06 | 2.06 |
| 427.53 | 2.67 | 2.67 |
| 454.53 | 1.16 | 1.16 |
| 427.53 | 2.67 | 2.67 |
| 441.55 | 2.98 | 2.98 |
| 451.52 | 1.92 | 1.92 |
| 452.51 | 1.31 | 1.31 |
| 428.51 | 2.07 | 2.07 |
| 488.49 | 2.17 | 2.17 |
| 465.52 | 0.01 | 0.01 |
| 506.60 | 2.89 | 2.89 |
| 428.56 | 2.85 | 2.85 |
| 461.97 | 3.33 | 3.33 |
| 451.52 | 2.62 | 2.62 |
| 436.51 | 2.32 | 2.32 |
| 422.49 | 2.01 | 2.01 |
| 487.56 | 3.87 | 3.87 |
| 458.54 | 2.08 | 2.08 |
| 466.54 | 1.70 | 1.70 |
| 468.51 | 0.69 | 0.69 |
| 452.51 | 1.31 | 1.31 |
| 436.51 | 1.82 | 1.82 |
| 441.55 | 2.98 | 2.98 |
| 428.51 | 2.07 | 2.07 |
| 452.56 | 2.18 | 2.18 |
| 451.52 | 1.92 | 1.92 |
| 451.53 | 2.05 | 2.05 |
| 399.52 | 2.76 | 2.76 |
| 438.53 | 1.79 | 1.79 |
| 452.51 | 1.31 | 1.31 |
| 422.49 | 2.01 | 2.01 |
| 427.53 | 2.67 | 2.67 |
| 421.50 | 2.61 | 2.61 |
| 466.54 | 1.79 | 1.79 |
| 503.62 | 4.34 | 4.34 |
| 454.48 | 1.28 | 1.28 |
| 442.54 | 2.38 | 2.38 |
| 468.51 | 0.69 | 0.69 |
| 452.48 | -0.90 | -0.90 |
| 485.61 | 2.49 | 2.49 |
| 424.50 | 1.39 | 1.39 |
| 466.54 | 1.62 | 1.62 |
| 452.51 | 2.02 | 2.02 |