Basic Information
ID: ALA4030854
Type: Binding
Description: Inhibition of UbcH5c (unknown origin) expressed in human 293T cells assessed as decrease in TNF-alpha-mediated NF-kB activation at 5 uM preincubated for 2 hrs followed by TNF-alpha stimulation for 8 hrs by luciferase reporter gene assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4030854
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 418.41 | 5.50 | 5.50 |
| 480.34 | 4.76 | 4.76 |
| 424.49 | 4.07 | 4.07 |
| 494.58 | 4.95 | 4.95 |
| 458.43 | 5.54 | 5.54 |
| 410.47 | 3.76 | 3.76 |
| 413.31 | 5.36 | 5.36 |
| 349.39 | 3.63 | 3.63 |
| 344.41 | 3.75 | 3.75 |
| 402.41 | 5.62 | 5.62 |
| 480.34 | 4.76 | 4.76 |
| 380.46 | 4.70 | 4.70 |
| 444.91 | 4.42 | 4.42 |
| 375.42 | 4.03 | 4.03 |