Basic Information
ID: ALA4030897
Type: Binding
Description: Inhibition of UbcH5c in mouse b.End3 cells assessed as decrease in TNF-alpha-mediated IkB-alpha degradation at 10 uM preincubated for 2 hrs followed by TNF-alpha stimulation for 20 mins by Western blot analysis
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4030897
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 480.34 | 4.76 | 4.76 |
| 424.49 | 4.07 | 4.07 |
| 410.47 | 3.76 | 3.76 |
| 413.31 | 5.36 | 5.36 |
| 349.39 | 3.63 | 3.63 |
| 248.32 | 2.21 | 2.21 |
| 344.41 | 3.75 | 3.75 |
| 480.34 | 4.76 | 4.76 |
| 444.91 | 4.42 | 4.42 |
| 375.42 | 4.03 | 4.03 |