Basic Information
ID: ALA4030998
Type: Binding
Description: Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase reporter gene assay
Format: BAO_0000219
Organism: Mus musculus
Target: GATA4/NKX2-5(ALA4106137)
Document: ALA4028856
Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4030998
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.24 | 2.58 | 2.58 |
| 286.24 | 2.28 | 2.28 |
| 349.43 | 4.75 | 4.75 |
| 233.29 | 2.57 | 2.57 |
| 397.86 | 4.39 | 4.39 |
| 302.40 | 3.39 | 3.39 |
| 336.39 | 4.69 | 4.69 |
| 427.48 | 2.92 | 2.92 |
| 326.40 | 3.33 | 3.33 |
| 336.39 | 4.69 | 4.69 |
| 413.48 | 4.89 | 4.89 |
| 363.42 | 3.74 | 3.74 |
| 338.44 | 3.87 | 3.87 |
| 330.46 | 3.90 | 3.90 |
| 354.44 | 3.57 | 3.57 |
| 382.49 | 4.35 | 4.35 |
| 346.35 | 2.88 | 2.88 |
| 298.34 | 3.15 | 3.15 |
| 321.40 | 3.54 | 3.54 |
| 334.42 | 5.42 | 5.42 |
| 324.41 | 2.58 | 2.58 |
| 337.77 | 4.43 | 4.43 |
| 413.50 | 3.93 | 3.93 |
| 318.44 | 3.84 | 3.84 |
| 427.53 | 4.24 | 4.24 |
| 296.37 | 3.32 | 3.32 |
| 321.38 | 4.33 | 4.33 |
| 381.51 | 3.97 | 3.97 |
| 337.45 | 3.81 | 3.81 |
| 260.34 | 2.42 | 2.42 |
| 435.47 | 3.49 | 3.49 |
| 290.36 | 2.19 | 2.19 |
| 376.41 | 4.94 | 4.94 |
| 318.38 | 4.39 | 4.39 |
| 361.45 | 4.89 | 4.89 |
| 314.21 | 4.01 | 4.01 |
| 364.40 | 4.47 | 4.47 |
| 323.43 | 3.63 | 3.63 |
| 334.42 | 5.20 | 5.20 |
| 290.41 | 3.45 | 3.45 |
| 310.38 | 3.12 | 3.12 |
| 361.83 | 4.17 | 4.17 |
| 381.51 | 3.97 | 3.97 |
| 361.40 | 3.79 | 3.79 |
| 340.41 | 3.13 | 3.13 |
| 262.35 | 2.81 | 2.81 |
| 325.41 | 4.37 | 4.37 |
| 277.35 | 3.14 | 3.14 |
| 336.42 | 3.55 | 3.55 |
| 288.27 | 2.57 | 2.57 |
| 222.25 | 3.40 | 3.40 |
| 368.86 | 6.07 | 6.07 |
| 322.36 | 4.30 | 4.30 |
| 339.42 | 3.30 | 3.30 |
| 320.39 | 5.03 | 5.03 |
| 324.41 | 3.43 | 3.43 |
| 372.45 | 4.91 | 4.91 |
| 298.35 | 3.26 | 3.26 |
| 375.45 | 5.33 | 5.33 |
| 411.48 | 3.69 | 3.69 |
| 337.45 | 3.81 | 3.81 |
| 250.24 | 1.92 | 1.92 |
| 368.86 | 5.85 | 5.85 |
| 370.41 | 5.69 | 5.69 |
| 390.47 | 4.79 | 4.79 |
| 294.38 | 3.42 | 3.42 |
| 320.39 | 3.48 | 3.48 |
| 303.38 | 3.81 | 3.81 |
| 422.47 | 3.50 | 3.50 |
| 324.41 | 3.51 | 3.51 |
| 437.48 | 3.97 | 3.97 |
| 364.40 | 4.47 | 4.47 |
| 302.42 | 3.59 | 3.59 |
| 357.53 | 4.34 | 4.34 |
| 362.31 | 4.80 | 4.80 |
| 304.42 | 3.19 | 3.19 |
| 293.32 | 2.30 | 2.30 |
| 422.55 | 5.08 | 5.08 |
| 337.38 | 3.52 | 3.52 |
| 364.47 | 4.44 | 4.44 |