Assay Report Card

Basic Information

ID: ALA4031038

Type: Binding

Description: Inhibition of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as decrease in endothelin-1 induced mRNA level of ANP at 20 uM preincubated for 1 hr followed by endothelin-1 addition measured after 23 hrs by real-time PCR analysis

Organism: Rattus norvegicus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
336.394.694.69
337.774.434.43
303.383.813.81
362.314.804.80