Basic Information
ID: ALA4031054
Type: ADME
Description: Prodrug activation in human Z138 cells assessed as 9-((2R,3R,4S,5R)-5-(((((2-(1H-Indol-3-yl)ethyl)amino)-(hydroxy)phosphoryl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-2-amino-7-(2-(4-chlorophenoxy)ethyl)-6-oxo-6,9-dihydro-1H-purin-7-ium formation per 5 million cells at 150 uM after 12 hrs by LC-MS/MS analysis
Organism: Homo sapiens
Cell type: Z-138
Activity Charts
Bioactivity
Activity Types for Assay ALA4031054
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 735.18 | 2.76 | 2.76 |