Basic Information
ID: ALA4031057
Type: ADME
Description: Prodrug activation in human Z138 cells assessed as Hint1 mediated 2-amino-7-(2-(4-chlorophenoxy)ethyl)-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-7-ium formation per 5 million cells at 150 uM after 12 hrs by LC-MS/MS analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4031057
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 735.18 | 2.76 | 2.76 |
| 661.03 | 1.38 | 1.38 |