Basic Information
ID: ALA4031105
Type: ADME
Description: Prodrug activation in Sprague-Dawley rat plasma assessed as 2-amino-7-(2-(4-chlorophenoxy)ethyl)-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-7-ium level at 2.5 mg/kg, iv measured at 5 mins by LC-MS/MS analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA4031105
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 661.03 | 1.38 | 1.38 |