Basic Information
ID: ALA4031136
Type: Binding
Description: Inhibition of C-terminal His-tagged full length Toxoplasma gondii CDPK1 expressed in Escherichia coli BL21 (DE3) using syntide-2 as substrate pre-incubated for 10 mins followed by ATP addition measured after 20 mins by ELISA
Format: BAO_0000019
Organism: Toxoplasma gondii
Target: Calmodulin-domain protein kinase 1(ALA1781862)
Document: ALA4028859
Inhibition of C-terminal His-tagged full length Toxoplasma gondii CDPK1 expressed in Escherichia coli BL21 (DE3) using syntide-2 as substrate pre-incubated for 10 mins followed by ATP addition measured after 20 mins by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4031136
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.34 | 3.03 | 3.03 |
| 315.81 | 3.41 | 3.41 |
| 358.83 | 2.85 | 2.85 |
| 319.31 | 3.23 | 3.23 |
| 333.85 | 3.97 | 3.97 |
| 330.78 | 2.07 | 2.07 |
| 359.82 | 3.28 | 3.28 |
| 354.48 | 2.87 | 2.87 |
| 394.81 | 3.10 | 3.10 |
| 344.81 | 2.46 | 2.46 |
| 373.91 | 3.82 | 3.82 |
| 313.36 | 2.96 | 2.96 |
| 358.40 | 2.28 | 2.28 |
| 372.82 | 2.38 | 2.38 |
| 316.80 | 3.56 | 3.56 |
| 317.78 | 3.61 | 3.61 |
| 352.79 | 3.30 | 3.30 |
| 410.88 | 3.46 | 3.46 |
| 374.90 | 3.21 | 3.21 |
| 372.86 | 3.20 | 3.20 |
| 358.83 | 2.85 | 2.85 |
| 297.36 | 3.26 | 3.26 |
| 376.82 | 2.99 | 2.99 |
| 356.86 | 2.65 | 2.65 |
| 351.33 | 3.97 | 3.97 |
| 357.85 | 2.81 | 2.81 |
| 383.76 | 4.20 | 4.20 |
| 362.23 | 3.72 | 3.72 |