Basic Information
ID: ALA4031180
Type: Binding
Description: Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presence of ATP and GTP after 30 mins by mass spectrometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4031180
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.29 | 0.92 | 0.92 |
| 213.20 | 0.89 | 0.89 |
| 312.33 | 1.21 | 1.21 |
| 268.28 | 1.46 | 1.46 |
| 380.40 | 2.48 | 2.48 |
| 298.30 | 0.82 | 0.82 |