Basic Information
ID: ALA4031182
Type: Binding
Description: Inhibition of cGAS in human THP1 cells assessed as reduction in salmon sperm dsDNA-induced IFN-beta expression preincubated for 1 hr followed by dsDNA stimulation for 12 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4031182
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 591.48 | 4.75 | 4.75 |
| 312.29 | 0.92 | 0.92 |
| 312.33 | 1.21 | 1.21 |
| 380.40 | 2.48 | 2.48 |
| 298.30 | 0.82 | 0.82 |