Basic Information
ID: ALA4031698
Type: Binding
Description: Inhibition of human GAT2 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4031698
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 354.45 | 3.10 | 3.10 |
| 344.46 | 4.23 | 4.23 |
| 294.40 | 3.08 | 3.08 |
| 338.45 | 3.48 | 3.48 |
| 363.29 | 4.39 | 4.39 |
| 364.28 | 3.78 | 3.78 |
| 364.28 | 3.78 | 3.78 |
| 273.16 | 2.48 | 2.48 |
| 338.41 | 2.81 | 2.81 |
| 408.29 | 4.30 | 4.30 |
| 364.28 | 3.78 | 3.78 |
| 391.30 | 4.07 | 4.07 |
| 489.18 | 4.99 | 4.99 |
| 389.33 | 4.90 | 4.90 |
| 451.33 | 4.84 | 4.84 |
| 413.35 | 5.54 | 5.54 |
| 287.19 | 2.82 | 2.82 |
| 387.31 | 3.53 | 3.53 |
| 315.24 | 3.60 | 3.60 |
| 331.20 | 2.27 | 2.27 |
| 340.25 | 3.49 | 3.49 |
| 311.21 | 2.82 | 2.82 |
| 362.39 | 4.10 | 4.10 |
| 364.28 | 3.78 | 3.78 |
| 312.39 | 3.22 | 3.22 |
| 260.38 | 2.42 | 2.42 |
| 421.32 | 4.17 | 4.17 |
| 388.30 | 4.26 | 4.26 |
| 414.34 | 4.94 | 4.94 |
| 388.30 | 4.26 | 4.26 |
| 301.22 | 3.21 | 3.21 |
| 408.29 | 4.30 | 4.30 |