Basic Information
ID: ALA4031701
Type: Binding
Description: Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting method
Format: BAO_0000219
Organism: Mus musculus
Target: GABA transporter 2(ALA4228)
Document: ALA4028872
Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4031701
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 328.84 | 3.73 | 3.73 |
| 363.29 | 4.39 | 4.39 |
| 364.28 | 3.78 | 3.78 |
| 447.28 | 5.29 | 5.29 |
| 408.33 | 4.18 | 4.18 |
| 407.30 | 2.88 | 2.88 |
| 359.86 | 3.14 | 3.14 |
| 447.28 | 5.29 | 5.29 |
| 329.83 | 3.13 | 3.13 |
| 328.84 | 3.73 | 3.73 |
| 295.39 | 2.48 | 2.48 |
| 422.31 | 3.57 | 3.57 |
| 325.41 | 2.48 | 2.48 |
| 370.31 | 3.84 | 3.84 |
| 300.43 | 3.14 | 3.14 |
| 440.37 | 5.45 | 5.45 |
| 391.34 | 5.00 | 5.00 |
| 364.27 | 4.81 | 4.81 |
| 393.31 | 4.40 | 4.40 |
| 403.31 | 4.26 | 4.26 |
| 474.36 | 5.71 | 5.71 |
| 408.29 | 3.51 | 3.51 |
| 377.32 | 4.70 | 4.70 |
| 424.33 | 3.15 | 3.15 |
| 295.38 | 3.51 | 3.51 |
| 423.34 | 4.41 | 4.41 |
| 380.27 | 3.49 | 3.49 |
| 397.73 | 5.04 | 5.04 |
| 295.39 | 2.48 | 2.48 |
| 431.29 | 5.41 | 5.41 |
| 394.30 | 3.79 | 3.79 |
| 329.83 | 3.13 | 3.13 |
| 349.30 | 4.75 | 4.75 |
| 359.86 | 3.14 | 3.14 |
| 408.29 | 3.48 | 3.48 |
| 329.83 | 3.13 | 3.13 |
| 325.41 | 2.48 | 2.48 |
| 432.18 | 5.69 | 5.69 |
| 330.45 | 3.15 | 3.15 |
| 409.27 | 3.69 | 3.69 |
| 381.28 | 4.53 | 4.53 |
| 397.73 | 5.04 | 5.04 |