Basic Information
ID: ALA4032324
Type: Binding
Description: Inhibition of LDH in human MIAPaCa2 cells assessed as reduction in lactate production preincubated for 2 hrs measured after 30 mins by high throughput fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Target: L-lactate dehydrogenase(ALA4105929)
Document: ALA4028893
Inhibition of LDH in human MIAPaCa2 cells assessed as reduction in lactate production preincubated for 2 hrs measured after 30 mins by high throughput fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4032324
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.30 | 3.71 | 3.71 |
| 497.57 | 3.40 | 3.40 |
| 285.33 | 3.00 | 3.00 |
| 649.63 | 5.66 | 5.66 |
| 305.29 | 2.54 | 2.54 |
| 287.30 | 2.40 | 2.40 |
| 494.60 | 3.88 | 3.88 |
| 317.33 | 2.41 | 2.41 |
| 373.74 | 4.37 | 4.37 |
| 532.60 | 4.30 | 4.30 |
| 499.06 | 5.56 | 5.56 |
| 517.59 | 3.99 | 3.99 |
| 373.74 | 4.37 | 4.37 |
| 323.28 | 2.68 | 2.68 |
| 476.49 | 3.21 | 3.21 |
| 328.35 | 2.65 | 2.65 |
| 288.29 | 1.79 | 1.79 |
| 337.36 | 3.55 | 3.55 |
| 293.35 | 2.78 | 2.78 |
| 313.38 | 3.82 | 3.82 |
| 321.75 | 3.05 | 3.05 |
| 531.62 | 4.18 | 4.18 |
| 517.59 | 4.75 | 4.75 |
| 355.30 | 3.42 | 3.42 |
| 305.29 | 2.54 | 2.54 |
| 288.29 | 1.79 | 1.79 |
| 441.49 | 3.09 | 3.09 |
| 492.49 | 2.92 | 2.92 |
| 373.74 | 4.37 | 4.37 |
| 363.40 | 4.07 | 4.07 |
| 323.28 | 2.68 | 2.68 |
| 516.60 | 4.60 | 4.60 |
| 357.29 | 3.85 | 3.85 |
| 305.29 | 2.54 | 2.54 |
| 570.70 | 5.55 | 5.55 |
| 558.64 | 5.68 | 5.68 |
| 535.40 | 3.40 | 3.40 |
| 480.57 | 3.81 | 3.81 |
| 440.51 | 2.93 | 2.93 |
| 517.59 | 3.99 | 3.99 |
| 371.30 | 3.30 | 3.30 |
| 321.31 | 3.63 | 3.63 |
| 323.28 | 2.68 | 2.68 |
| 356.19 | 3.71 | 3.71 |
| 286.32 | 2.28 | 2.28 |
| 550.59 | 4.44 | 4.44 |
| 556.67 | 5.48 | 5.48 |
| 584.60 | 5.62 | 5.62 |
| 381.39 | 4.21 | 4.21 |