Basic Information
ID: ALA4032663
Type: Binding
Description: Agonist activity at human FXR expressed in HEK293T cells assessed as BSEP promoter driven cellular transcriptional activity after 24 hrs by luciferase reporter gene assay relative to GW4064
Organism: Homo sapiens
Cell type: HEK-293T
Activity Charts
Bioactivity
Activity Types for Assay ALA4032663
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.63 | 5.11 | 5.11 |
| 587.60 | 7.40 | 7.40 |
| 573.59 | 7.00 | 7.00 |
| 603.59 | 7.28 | 7.28 |
| 559.57 | 6.61 | 6.61 |
| 531.51 | 5.83 | 5.83 |
| 544.46 | 7.02 | 7.02 |
| 543.57 | 6.73 | 6.73 |
| 615.63 | 7.15 | 7.15 |
| 585.60 | 6.98 | 6.98 |
| 585.60 | 7.14 | 7.14 |
| 530.43 | 6.63 | 6.63 |
| 511.55 | 5.99 | 5.99 |
| 599.63 | 7.45 | 7.45 |