Basic Information
ID: ALA4032894
Type: Binding
Description: Allosteric inhibition of 2P-IRS-1 stimulated wild type SHP2 (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrate addition measured after 20 mins by phosphatase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4032894
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 352.27 | 3.35 | 3.35 |
| 402.36 | 5.04 | 5.04 |