Assay Report Card

Basic Information

ID: ALA4032906

Type: Binding

Description: Allosteric inhibition of SHP2 in human NCI-H661 cells assessed as downregulation of phosphorylated ERK1/2 levels at 2.5 to 20 uM after 2 hrs by Western blot analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
402.365.045.04