Basic Information
ID: ALA4032944
Type: Binding
Description: Allosteric inhibition of SHP2 E76A mutant (unknown origin) assessed as reduction in SHP2-mediated YAP Y357 peptide dephosphorylation. preincubated for 15 mins before YAP pY357 peptide addition and measured after 15 mins post substrate addition
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4032944
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 402.36 | 5.04 | 5.04 |