Basic Information
ID: ALA4033368
Type: Binding
Description: Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP addition measured after 60 mins by Z'-Lyte assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase PAK 4(ALA4482)
Document: ALA4028914
Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP addition measured after 60 mins by Z'-Lyte assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4033368
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.44 | 2.55 | 2.55 |
| 385.86 | 2.49 | 2.49 |
| 385.90 | 3.80 | 3.80 |
| 399.89 | 2.88 | 2.88 |
| 411.90 | 3.06 | 3.06 |
| 397.87 | 2.67 | 2.67 |
| 385.86 | 2.45 | 2.45 |
| 407.48 | 2.42 | 2.42 |
| 385.86 | 2.49 | 2.49 |
| 385.86 | 2.62 | 2.62 |
| 419.92 | 4.14 | 4.14 |
| 399.89 | 2.88 | 2.88 |
| 399.89 | 2.88 | 2.88 |
| 383.89 | 3.55 | 3.55 |
| 425.92 | 3.45 | 3.45 |
| 385.86 | 2.54 | 2.54 |
| 411.90 | 3.06 | 3.06 |
| 400.87 | 3.05 | 3.05 |
| 385.86 | 2.49 | 2.49 |
| 411.90 | 3.06 | 3.06 |
| 357.85 | 2.69 | 2.69 |
| 357.81 | 1.76 | 1.76 |
| 456.35 | 3.17 | 3.17 |
| 411.90 | 3.06 | 3.06 |
| 425.92 | 3.45 | 3.45 |
| 357.85 | 2.99 | 2.99 |
| 372.82 | 2.53 | 2.53 |
| 419.92 | 4.34 | 4.34 |
| 371.83 | 2.10 | 2.10 |
| 385.82 | 1.63 | 1.63 |
| 385.86 | 2.49 | 2.49 |
| 386.84 | 2.66 | 2.66 |
| 385.90 | 3.73 | 3.73 |
| 411.90 | 3.06 | 3.06 |
| 399.89 | 2.88 | 2.88 |
| 377.45 | 2.41 | 2.41 |
| 383.89 | 3.49 | 3.49 |
| 399.89 | 3.01 | 3.01 |