Basic Information
ID: ALA4033426
Type: Binding
Description: Antagonist activity at rat recombinant P2X7 expressed in 1321N1 cells assessed as inhibition of BzATP-induced calcium mobilization after 30 mins by calcium-4 staining based FLIPR assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4033426
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.79 | 3.46 | 3.46 |
| 420.37 | 3.11 | 3.11 |
| 425.32 | 2.34 | 2.34 |
| 424.33 | 2.94 | 2.94 |
| 422.80 | 3.32 | 3.32 |
| 421.81 | 3.92 | 3.92 |
| 421.36 | 2.51 | 2.51 |
| 420.82 | 4.53 | 4.53 |
| 441.78 | 2.85 | 2.85 |
| 438.84 | 3.74 | 3.74 |
| 439.83 | 3.14 | 3.14 |
| 426.85 | 4.59 | 4.59 |
| 438.84 | 3.74 | 3.74 |
| 396.31 | 1.53 | 1.53 |
| 423.33 | 1.90 | 1.90 |