Basic Information
ID: ALA4033433
Type: ADME
Description: Inhibition of CYP2C9 in human liver microsomes using tolbutamide or diclofenac as substrates
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4033433
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.32 | 2.34 | 2.34 |
| 424.33 | 2.94 | 2.94 |
| 422.80 | 3.32 | 3.32 |
| 421.81 | 3.92 | 3.92 |
| 421.36 | 2.51 | 2.51 |
| 420.82 | 4.53 | 4.53 |
| 439.83 | 3.14 | 3.14 |
| 426.85 | 4.59 | 4.59 |
| 438.84 | 3.74 | 3.74 |
| 396.31 | 1.53 | 1.53 |
| 423.33 | 1.90 | 1.90 |