Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calci...

Basic Information

ID: ALA4033578

Type: Binding

Description: Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calcium flux by fluo-4/AM dye-based fluorescence assay

Format: BAO_0000219

Organism: Homo sapiens

Target: Glutamate receptor ionotropic, AMPA 2(ALA4016)

Document: ALA4028918

Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calcium flux by fluo-4/AM dye-based fluorescence assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4033578

EC50

Total(38)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
213.26	0.16	0.16
264.71	1.37	1.37
242.28	1.04	1.04
320.37	2.17	2.17
320.37	2.17	2.17
330.41	3.01	3.01
341.39	2.57	2.57
304.37	2.47	2.47
346.41	2.71	2.71
260.75	1.76	1.76
330.41	3.01	3.01
346.41	2.71	2.71
304.37	2.47	2.47
330.41	3.01	3.01
320.37	2.17	2.17
304.37	2.47	2.47
346.41	2.71	2.71
290.34	2.16	2.16
316.38	2.70	2.70