Basic Information
ID: ALA4033995
Type: Binding
Description: Inhibition of HDAC1/2 in human HeLa cell nuclear extract using COLOR DE LYS as substrate pretreated for 5 mins followed by substrate addition measured after 30 mins by UV-absorption method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Histone deacetylase (HDAC1 and HDAC2)(ALA2111429)
Document: ALA4033620
Inhibition of HDAC1/2 in human HeLa cell nuclear extract using COLOR DE LYS as substrate pretreated for 5 mins followed by substrate addition measured after 30 mins by UV-absorption method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4033995
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 502.37 | 5.36 | 5.36 |
| 487.94 | 5.26 | 5.26 |
| 453.54 | 4.96 | 4.96 |
| 467.53 | 4.54 | 4.54 |
| 502.41 | 5.72 | 5.72 |
| 397.48 | 4.56 | 4.56 |
| 363.42 | 3.05 | 3.05 |
| 412.29 | 3.81 | 3.81 |
| 502.37 | 5.36 | 5.36 |
| 496.45 | 6.10 | 6.10 |
| 516.40 | 5.29 | 5.29 |
| 333.39 | 3.04 | 3.04 |
| 453.50 | 4.61 | 4.61 |
| 307.35 | 2.64 | 2.64 |
| 341.80 | 3.30 | 3.30 |
| 423.52 | 4.96 | 4.96 |
| 453.50 | 4.61 | 4.61 |
| 363.42 | 3.05 | 3.05 |
| 502.41 | 5.72 | 5.72 |
| 423.47 | 4.60 | 4.60 |
| 496.45 | 6.10 | 6.10 |
| 337.38 | 2.65 | 2.65 |
| 367.84 | 3.70 | 3.70 |
| 367.84 | 3.70 | 3.70 |
| 412.29 | 3.81 | 3.81 |
| 437.50 | 4.53 | 4.53 |
| 386.25 | 3.41 | 3.41 |
| 457.96 | 5.61 | 5.61 |