Basic Information
ID: ALA4034991
Type: Functional
Description: In-vivo inhibition of Chk2 in MNU-induced breast cancer in Sprague-Dawley rat assessed as enzyme activity at 0.1 times LD50 administered orally for 10 consecutive days followed by single dose of doxorubicin at 2 mg/kg, ip measured after 30 days by ELISA based spectrophotometric analysis (Rvb = 1.99 +/- 0.21 mU)
Format: BAO_0000218
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Target: Rattus norvegicus(ALA376)
Document: ALA4033655
In-vivo inhibition of Chk2 in MNU-induced breast cancer in Sprague-Dawley rat assessed as enzyme activity at 0.1 times LD50 administered orally for 10 consecutive days followed by single dose of doxorubicin at 2 mg/kg, ip measured after 30 days by ELISA based spectrophotometric analysis (Rvb = 1.99 +/- 0.21 mU): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4034991
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 455.43 | 5.12 | 5.12 |
| 496.53 | 5.56 | 5.56 |