Basic Information
ID: ALA4035077
Type: Binding
Description: Antagonist activity at human TLR9 expressed in HEK293 cells assessed as inhibition of CpGB-induced NF-kappaB activation after 24 hrs by spectrophotometry based SEAP reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Toll-like receptor 9(ALA5804)
Document: ALA4033660
Antagonist activity at human TLR9 expressed in HEK293 cells assessed as inhibition of CpGB-induced NF-kappaB activation after 24 hrs by spectrophotometry based SEAP reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4035077
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.36 | 4.16 | 4.16 |
| 456.55 | 5.19 | 5.19 |
| 449.60 | 5.22 | 5.22 |
| 405.54 | 4.83 | 4.83 |
| 479.63 | 3.10 | 3.10 |
| 403.53 | 4.74 | 4.74 |
| 322.41 | 4.36 | 4.36 |
| 390.41 | 5.38 | 5.38 |
| 434.58 | 4.87 | 4.87 |
| 470.57 | 5.07 | 5.07 |
| 420.56 | 4.52 | 4.52 |
| 322.41 | 4.36 | 4.36 |
| 441.53 | 5.61 | 5.61 |
| 443.51 | 4.83 | 4.83 |
| 510.68 | 6.44 | 6.44 |
| 498.63 | 5.67 | 5.67 |
| 477.65 | 6.00 | 6.00 |