Basic Information
ID: ALA4035080
Type: Binding
Description: Antagonist activity at human TLR7 expressed in HEK293 cells assessed as inhibition of CL264-induced NF-kappaB activation after 24 hrs by spectrophotometry based SEAP reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Toll-like receptor 7(ALA5936)
Document: ALA4033660
Antagonist activity at human TLR7 expressed in HEK293 cells assessed as inhibition of CL264-induced NF-kappaB activation after 24 hrs by spectrophotometry based SEAP reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4035080
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 449.60 | 5.22 | 5.22 |
| 405.54 | 4.83 | 4.83 |
| 479.63 | 3.10 | 3.10 |
| 403.53 | 4.74 | 4.74 |
| 434.58 | 4.87 | 4.87 |
| 470.57 | 5.07 | 5.07 |
| 420.56 | 4.52 | 4.52 |
| 510.68 | 6.44 | 6.44 |
| 498.63 | 5.67 | 5.67 |