Basic Information
ID: ALA4035162
Type: Binding
Description: Inhibition of IL-6 signaling pathway in human HepG2 cells transfected with p-STAT3-Luc assessed as reduction in IL-6 induced STAT3 phosphorylation at 20 ug/ml preincubated for 1 hr followed by IL-6 induction measured after 10 mins by immunoblot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4035162
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 516.52 | 8.15 | 8.15 |
| 391.86 | 6.04 | 6.04 |
| 253.31 | 3.72 | 3.72 |
| 436.86 | 5.95 | 5.95 |
| 443.40 | 6.54 | 6.54 |
| 447.49 | 5.41 | 5.41 |
| 436.86 | 5.95 | 5.95 |
| 426.30 | 6.69 | 6.69 |
| 405.89 | 6.12 | 6.12 |
| 357.41 | 5.39 | 5.39 |
| 413.52 | 6.68 | 6.68 |
| 385.47 | 5.95 | 5.95 |
| 401.47 | 5.78 | 5.78 |
| 455.60 | 7.90 | 7.90 |
| 371.44 | 5.32 | 5.32 |
| 417.47 | 5.40 | 5.40 |