Basic Information
ID: ALA4035163
Type: Binding
Description: Inhibition of IL-6 signaling pathway in human HepG2 cells transfected with p-STAT3-Luc assessed as reduction in IL-6 induced STAT3 phosphorylation preincubated for 1 hr followed by IL-6 induction measured after 10 mins by immunoblot analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Interleukin-6(ALA1795129)
Document: ALA4033664
Inhibition of IL-6 signaling pathway in human HepG2 cells transfected with p-STAT3-Luc assessed as reduction in IL-6 induced STAT3 phosphorylation preincubated for 1 hr followed by IL-6 induction measured after 10 mins by immunoblot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4035163
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 253.31 | 3.72 | 3.72 |
| 357.41 | 5.39 | 5.39 |
| 367.49 | 4.09 | 4.09 |