Basic Information
ID: ALA4035268
Type: ADME
Description: Inhibition of recombinant human CYP3A4 expressed in baculosomes using BOMR as substrate preincubated for 10 mins followed by substrate/NADP+ addition measured for 1 hr
Format: BAO_0000019
Organism: Homo sapiens
Target: Cytochrome P450 3A4(ALA340)
Document: ALA4033666
Inhibition of recombinant human CYP3A4 expressed in baculosomes using BOMR as substrate preincubated for 10 mins followed by substrate/NADP+ addition measured for 1 hr: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4035268
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 448.32 | 4.56 | 4.56 |
| 383.46 | 4.11 | 4.11 |
| 387.42 | 3.94 | 3.94 |
| 403.87 | 4.45 | 4.45 |
| 385.43 | 3.51 | 3.51 |
| 414.43 | 3.71 | 3.71 |