Basic Information
ID: ALA4035293
Type: Binding
Description: Inhibition of human DNA topoisomerase 2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA at 0.5 to 5 uM after 1 hr by ethidium bromide staining-based agarose gel electrophoresis
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4033667
Inhibition of human DNA topoisomerase 2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA at 0.5 to 5 uM after 1 hr by ethidium bromide staining-based agarose gel electrophoresis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4035293
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 313.31 | 1.91 | 1.91 |
| 588.56 | 1.34 | 1.34 |
| 385.32 |